New Drugs Show Potential Against Breast Cancer

ORLANDO (Dow Jones)--Two studies looking at a new type of drug being designed to cause cancer cells to die in a different way than currently available drugs showed potential as a therapy for hard-to-treat types of breast cancer.

One study involved women with so-called triple negative breast cancer, which means the tumors lack receptors for estrogen, progesterone and HER2, and involved a drug known as BSI-201, that's being developed by a unit of Sanofi Aventis SA (SNY). The other study looked at women with breast cancer patients with BRCA gene mutations which also makes that type of cancer difficult to treat and involved a drug known as olaparib, which is being developed by AstraZeneca PLC (AZN). The studies were presented Sunday at the American Society of Clinical Oncology's annual meeting.

The On-line Medical Dictionary

The On-line Medical Dictionary
OMD is a searchable dictionary created by Dr Graham Dark and contains terms relating to biochemistry, cell biology, chemistry, medicine, molecular biology, physics, plant biology, radiobiology, science and technology. It includes: acronyms, jargon, theory, conventions, standards, institutions, projects, eponyms, history, in fact anything to do with medicine or science.It aims to provide a one-stop source of information about all medical and scientific terms and includes many useful cross-references and pointers to related resources elsewhere on the Internet, as well as bibliographical reference to paper publications. It lacks many entries which one can find in paper dictionaries but contains more encyclopaedia-like entries and entries on various subjects. It also contains many definitions in related areas.The dictionary started in early 1997 and has grown, to contain over 46,000 definitions totalling 17.5 megabytes. Entries are cross-referenced to each other and to related resources elsewhere on the net. It is freely available on the Internet via the World-Wide Web.All searches are logged and a list of frequently requested missing terms is checked. Users are encouraged to contribute definitions of missing terms. These contributions are usually edited extensively before inclusion. New terms are added almost every day.The dictionary is stored as a single source file in a simplified, easy-to-edit, human-readable form of mark-up which is converted to HTML on the fly by a Perl CGI script originally developed by Denis Howe at Imperial College for the Free On-Line Dictionary of Computing. The script uses Perl's extensive regular expression matching facilities to provide fast, indexed searches of headings as well as full-text searches. Other bits of the Perl script are used off-line to generate the lists of missing terms and the contents pages. It is hoped to develop this further to allow maintenance of the dictionary and associated files through a web form-based interface.Dates after entries indicate when that entry was created, updated or first date-stamped. They do not imply that it was up-to-date at that time.

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